Investigation of Combined Treatment of Acupuncture and Neurofeedback for Improving Cognitive Function in Mild Neurocognitive Disorder

Investigation of Combined Treatment of Acupuncture and Neurofeedback for Improving Cognitive Function in Mild Neurocognitive Disorder: a randomized, assessor-blind, pilot study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0004972

Enrollment

Registered

2020-04-28

Start date

2020-08-18

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others : Subjects are randomized into combined treatment of acupuncture and neurofeedback or acupuncture treatment. Combined treatment of acupuncture and neurofeedback: acupuncture treatment on GV20,

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Mild Neurocognitive Disorder patients who meet Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) criteria 2) Korean version of Montreal Cognitive Assessment (MoCA-K) scores less than 22 3) Education level of more than 6 years 4) Participants who understood the purpose of this study and voluntarily signed the informed consent form

Exclusion criteria

Exclusion criteria: 1) Alzheimer, vascular dementia, Parkinson's disease, huntington's disease, hydrocephalus 2) Presenting mental disorder including schizophrenia, delusional disorder, major depressive disorder, bipolar disorder, alcohol dependence, substance-related disorders, and etc. based on DSM-5 3) Presence or history of neurological disorders, including epilepsy, regional brain damage, head injury, stroke, and etc. 4) Receiving treatments or participating other clinical study within the last 4 weeks due to Mild Neurocognitive Disorder 5) Having test for Mild Neurocognitive Disorder within the last 12 weeks 6) Pregnant or lactating women 7) Unstable medical state (assessment by research doctor with vital signs, laboratory test, ECG test) 8) Hypertension, blood pressure excessing 160mmHg systolic and 95mmHg diastolic 9) Significant liver disease or excessing serum AST, ALT, ?-GTP levels than twice over references 10) Unavailable to measure f-NIRS 11) Disagreement with acupuncture treatment 12) Participant, who is probably uncooperative in the study or judged by researcher as difficult to finish the study

Design outcomes

Primary

Measure	Time frame
Korean version of Montreal Cognitive Assessment (MoCA-K) score	—

Secondary

Measure	Time frame
Korean version of Beck's Depression Inventory (K-BDI) score;The Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-cog) score;Oxy-Hb and deOxy-Hb in frontal lobe measured by functional Near-Infrared Spectroscopy (fNIRS);Accuracy of working memory task	—

Countries

Korea, Republic of

Contacts

Public ContactChangjin Jung

Korea Institute of Oriental Medicine

traviswas@kiom.re.kr+82-42-868-9368

Outcome results