The purpose of this study is to investigate the effects of dexamethasone gargle and intravenous infusion, respectively, and relief of postoperative sore throat when both methods are used simultaneously.

Effect of Gargling with dexamethasone, Intravenous dexamethasone and their combination on Postoperative Sore Throat

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0004971

Enrollment

Registered

2020-04-28

Start date

2019-09-09

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : The study will be conducted in a total of 96 patients divided into 3 groups. The first group is the Gargle group (Group G). 10 minutes before anesthesia, the patient will be fully leaned back a

dexamethasone solution (Dexamethasone 5 mg / ml + 0.9&#37

Normal saline 9 ml) for 30 seconds. 5 minutes before anesthesia, 2 ml of 0.9&#37

Normal saline will be injected intravenously. In the second group, IV group (Group I), 10 minutes before anesthesia, the patient will be fully leaned back and gargle with 0.9&#37

Normal saline for 30 seconds. 5 minutes before anesthesia, 2 ml mixed solution (Dexamethasone 0.1 mg/kg + 0.9&#37

normal saline) will be injected intravenously. In the third group, Gargle + IV (Group GI), 10 minutes before anesthesia, the patient will be fully leaned back and gargle with 0.05&#37

Normal saline 9 ml) for 30 seconds. 5 minutes before anesthesia, 2 ml mixed solution (Dexamethasone 0.1 mg/kg + 0.9&#37

normal saline) will be injected intravenously.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. 20-70 yr old 2. ASA ? or ? 3. Laparoscopic cholecystectomy 4. Scheduled for elective surgery 5. Anesthetic time > 20 min and < 120 min

Exclusion criteria

Exclusion criteria: 1. Patient who experienced POST due to previous operation 2. Patient with recent upper respiratory infection symptom 3. Patient with Levin tube or Endoscopic nasobiliary drainage 4. Intubated with more than two attempt 5. Blood tinged tube at extubation

Design outcomes

Primary

Measure	Time frame
Postoperative sore throat	—

Secondary

Measure	Time frame
Hoarseness	—

Countries

Korea, Republic of

Contacts

Public ContactJeong han Lee

Inje University Busan Paik Hospital

Outcome results