The effect of opioid-free general anesthesia on the gynecological laparoscopy

The effect of opioid-free general anesthesia on the perioperative inflammation and postoperative outcomes in patients undergoing gynecological laparoscopy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0004941

Enrollment

100

Registered

2020-04-20

Start date

2020-05-06

Completion date

Unknown

Last updated

2022-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : study group: dexmedetomidine 0.1-1.0 ug/kg/hr intravenous infusion during general anesthesia control group: remifentanil 0.05-0.2 ug/kg/min intravenous infusion during general anesthesia

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: patient scheduled for gynecological laparoscopic surgery

Exclusion criteria

Exclusion criteria: 1. patient who refuse to participate in this study 2. emergent surgery 3. chronic pain requiring for pain killer 4. psychiatric disease 5. immunologic disease (eg. SLE, Rheumatoid arthritis) 6. contraindication to dexmedetomidine: bradycardia or hypotension 7. allergy or history of the adverse effect to study drug 8. pregnancy or lactation

Design outcomes

Primary

Measure	Time frame
acute pain severity in the recovery room	—

Secondary

Measure	Time frame
opioid associated side effects (nasea, vomiting, sedation, constipation)	—

Countries

Korea, Republic of

Contacts

Public ContactMoon Youngeun

The Catholic University of Korea, Seoul St. Mary's Hospital

0910momo@naver.com+82-2-2258-6163

Outcome results