Pheniramine and catheter-related bladder discomfort

Effect of chlorpheniramine on postoperative catheter-related bladder discomfort

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0004880

Enrollment

Registered

2020-04-03

Start date

2020-05-01

Completion date

Unknown

Last updated

2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : After anesthetic induction, chlorpheniramine 5-10 mg will be injected intravenously in the experimental group. After anesthetic induction, normal saline 1ml will be injected intravenously in th

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients scheduled transurethral bladder resection or transurethral prostate resection under general anesthesia with informed consent 2. Patients aged 19-80 years with Americal Society of Anesthesiologists physical status classification system I-III

Exclusion criteria

Exclusion criteria: 1. Patients who does not consent to the trial 2. Pregnancy 3. Patients with foley catheter (<18 Fr.) 4. Patients with the obstruction of urinary tract 5. Patients with overactive, neurogenic bladder 6. Patients with body mass index > 35 kg/m2 7. Patients with analgesic usage due to chronic pain 8. Patients with hypersensitivity to chlorpheniramine 9. Patients with seizure

Design outcomes

Primary

Measure	Time frame
Catheter-related bladder discomfort at postoperative 1 hour	—

Secondary

Measure	Time frame
Hypotension in the postanesthesia care unit;Catheter-related bladder discomfort at postoperative 6, 24 hour;Suprapuvic pain;Nausea;Vomiting;Dry mouth;Flushing;Dizziness;Blurred vision;Sedation scale	—

Countries

Korea, Republic of

Contacts

Public ContactHyun-Chang Kim

Korea University Anam Hospital

Outcome results