Early administration of denosumab of distal radius fracture after volar plate fixation

Early administration of denosumab did not affect the bone healing and clinical outcome of distal radius fracture after volar plate fixation: A Prospective Randomized Study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0004872

Enrollment

Registered

2020-04-02

Start date

2020-04-08

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Experimental group: Denosumab injection was conducted within 48 hours post-operatively. Control group: Denosumab injection was conducted 3 months after the operation.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: After approving Institutional Review Board, all women older than fifty years of age with a distal radial fracture treated with volar locking plating were recruited. Among them, those who had a T-score of <-2.5 were finally included.

Exclusion criteria

Exclusion criteria: (1) Patients who refused to treated with denoxumab (2) Patients who require bone graft or bone substitute due to open fractures or severe communited fractures (3) Patients who underwent surgery after 2 weeks (4) People with disabilities in bone metabolism (5) Patientswho underwent operation with additional fixation method other than volar plating

Design outcomes

Primary

Measure	Time frame
The time to healing of the fracture, Radius union scoring system	—

Secondary

Measure	Time frame
Radiologic parameters and clinical outcome based on the Disabilities of the Arm, Shoulder and Hand Score, the Patient-Rated Wrist Evaluation, Range of motion and Grip strength	—

Countries

Korea, Republic of

Contacts

Public ContactHyoung Seok Jung

Chung-Ang Univerisity Hospital

ksjhs5739@naver.com+82-2-6299-3103

Outcome results