None listed
Conditions
Interventions
None listed
Sponsors
Kyungpook National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: sudden hearing loss A. Hearing loss [30 dB in 3 consecutive frequency within 72 h] B. Sudden hearing loss must be unilateral. Noise-induced hearing loss- trensient threshold shift) A. A temporary shift in the auditory threshold suddenly after exposure to a high level of noise Common inclusion criteria A. No initial treatment before; B. Must apply within 2 weeks after onset; C. Age more than 20 years
Exclusion criteria
Exclusion criteria: A. Presence of acute or chronic otitis media; B. Had previous otologic surgery; C. Trauma; D. Presence of a neoplasm; E. Recent application of radiotherapy and/or chemotherapy; F. Recent use of ototoxic drugs; G. Syphilis; H. Retro-cochlear lesion. I. Age < 20 years J. Pregnant, lactating, possibly pregnant women K. Cisplatin user L. Severe liver disease or kidney disease M. Uncontrolled DM N. Active infectious disease ( e.g. herpes zoster, chicken pox, tuberculosis) O. Cataract, glaucoma, severe osteoporosis P. Seizure, myasthenia gravis Q. Hypothyroidism, congestive heart disease R. Recent bowl surgery S. Ischemic heart disease, embolism. T. Patients who have hypersensitivity reaction of alpha-lipoic acid or steroid
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effect of treatment with steroid therapy and alpha-lipoic acid in combination with sudden hearing loss or noise-induced hearing loss over time and the results of pure tone hearing threshold (change in pure tone hearing threshold by frequency) | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in speech discernment | — |
Countries
Korea, Republic of
Contacts
Public Contactda jung Jung
Kyungpook National University Hospital
Outcome results
None listed