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Evaluation of endocrine complications in patients with long-term epidural steroid injections

A clinical research for hypothalamus-pituitary-adrenal axis suppression and development of Cushing’s syndrome after long-term epidural steroid injection

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0004828
Enrollment
30
Registered
2020-03-13
Start date
2014-06-02
Completion date
Unknown
Last updated
2020-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

The Catholic University of Korea, Yeouido St. Mary's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) The subject is a classification method that predicts the risk of anesthesia based on the health condition of patients scheduled for surgery that is determined by the American Association of anesthesiologists (ASA) category 1. That is, class 1 is in a state of no internal disease. Anesthesia-related journals should be free from other underlying conditions, customarily used as an indicator of the health of the subject. 2) The patient is over 50 years old, and gender is irrelevant (but women are menopause patients) 3) Patients diagnosed with lumbar HNP or spinal stenosis based on symptoms (pain nature, pain location, intermittent neurogenic claudication, pain aggravating or relieving factors, etc.), signs (straight leg raising test, sensory, motor, deep tendon reflex, etc.), and magnetic resonance imaging (MRI) findings. 4) The person is willing and able to sign a written agreement to participate in this test and fully understand and cooperate with the test.

Exclusion criteria

Exclusion criteria: 1) Patients with absolute maladaptation of the ESI (blood clotting disorder patients, infected patients in the area of the procedure) 2) Patients who are maladaptive of steroids (those who overreact to steroids, pregnant women, and those who have endocrine diseases) 3) Patients who have received steroid treatment for other conditions over the past three months 4) Chronic disease such as diabetes, high blood pressure, heart failure, kidney disease, liver disease 5) Sleep pattern is abnormal 6) Those who are taking hormone preparations such as oriental medicine and contraceptives 7) Those who have experienced severe stress for the past month 8) The subjects with oral disease. 9) The subjects should not drink alcohol for up to 12 hours before sampling. 10) The subjects do not eat or drink food until one hour after sampling.

Design outcomes

Primary

MeasureTime frame
salivary cortisol concentration

Secondary

MeasureTime frame
ACTH stimulation test;Late-night salivary cortisol (LNSC) measurement;Numeric rating scale (NRS) score;Serum ACTH;Fasting blood sugar

Countries

Korea, Republic of

Contacts

Public ContactHo Sik Moon

The Catholic University of Korea, Eunpyeong St. Mary's Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026