None listed
Conditions
Interventions
Dietary Supplement : Treatment: Capsule that contains the ME-100(2 capsules/time, 1 times/ day)
Placebo: Placebo capsule that contains mainly crystalline cellulose without ME-100
(2 capsules/time, 1 t
Sponsors
Kyung Hee University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Subject who voluntarily agree to participate and signs informed consent form 2) Men and women aged 30 to under 60 3) Subject who has a dry skin (skin moisture content index below 49AU measured using Corneometer®), eye wrinkles begin to form or have already formed (visual evaluation grade 3 or higher).
Exclusion criteria
Exclusion criteria: 1) Subjects with abnormal skin conditions such as spots, acne, erythema, and capillary dilation in the test area 2) Subjects who have or are currently undergoing treatment for skin diseases such as atopic dermatitis and psoriasis 3) Subjects who take contraceptives or hormones or diuretics 4) Subjects who take a oral retinoid/steroid agent or use a skin external substance containing steroids or retinoids within 3 months before the first visit 5) Subjects who use a functional cosmetic (retinoid agent, retinol, AHA) to improve wrinkles or moisturizing cosmetic within 2 weeks before the first visit 6) Subjects who received treatment(skin stripping, lazer, chemical peeling, other skin care, etc.) on the facial area within 1 month or received treatment(botox, filler) on the facial area within 6 months before the first visit 7) Subjects with diseases such as uncontrolled hypertension, uncontrolled diabetes, renal dysfunction, liver dysfunction, etc. 8) Subjects who have been continuously consumed any healthy functional food within 1 month before the first visit 9) Smokers or Subjects who smoke less than a year after quitting smoking 10) Participation in other human study within 1 month before the first visit 11) Subjects who are pregnant, nursing, or planning to conceive 12) Subjects with hypersensitivity to test materials 13) Any condition that the principal investigator believes may put the subjects at undue risk
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin moisture content, Transepidermal water loss, Keratin mass, Skin elasticity, Skin texture, Eye wrinkle;General improvement self evaluation | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical laboratory test(blood, urine);Adverse events | — |
Countries
Korea, Republic of
Contacts
Public ContactSinai Lee
Kyung Hee University
Outcome results
None listed