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The Prognostic Value of Biomarkers in Adult Moderate to Severe Traumatic Brain Injury Patients

The Prognostic Value of Biomarkers in Adult Moderate to Severe Traumatic Brain Injured Patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0004811
Enrollment
92
Registered
2020-03-09
Start date
2020-02-29
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Asan Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age =18 years and = 80 years 2. Acute traumatic brain injury; Diffuse axonal injury, subarachnoid hemorrhage (non-aneurysmal rupture); intracranial or intraventricular hemorrhage, subdural hematoma, epidural hematoma (either primary or anticoagulants-associated) 3. Moderate to severe traumatic brain injury (TBI): Glasgow Coma Scale (GCS) of 3 – 12

Exclusion criteria

Exclusion criteria: 1. Post-anoxic coma; status epilepticus without underlying brain injury; central nervous system (CNS) infections (community-acquired; hospital-acquired; ventriculitis; post-operative) 2. Known previous neurological disease, causing significant cognitive and/or motor handicap 3. Hemorrhage due to arterio-venous malformation (AVM), cavernous malformation (CM), cerebral aneurysm rupture or brain tumor 4. Hypertensive ICH or IVH 5. Pregnancy or Nephrotic syndrome diagnosed patient 6. DNR (do not resuscitate) orders

Design outcomes

Primary

MeasureTime frame
Glasgow Coma Scale;Modified Rankin Scale;Korean mini mental status (K-MMSE);Korean Montreal Cognitive Assessment [K-MoCA];Center for Epidemiologic Studies – Depression Scale [CES-D]

Secondary

MeasureTime frame
Days of ICU stay;Need for tracheostomy

Countries

Korea, Republic of

Contacts

Public ContactMoinay Kim

University of Ulsan

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026