None listed
Conditions
Interventions
Others(HMR care foods) : 1. healthy adults : people who fasting blood glucose and postprandial blood glucose are within normal range
2. pre-diabetes adults : people who fasting blood glucose is from 1
Sponsors
Chonbuk National University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Those who are between 19 and 70 years old at the time of screening test 2) Persons with a BMI of 18.5 kg / m² or more and less than 35 kg / m² 3) Those whose blood glucose level meets one of the following criteria (1) Healthy adults: those with fasting and postprandial blood sugar in the normal range (less than 100 mg / dl fasting glucose, less than 140 mg / dl blood glucose 2 hours oral glucose test) (2) pre-diabetic adults : 100-125 mg / dL of fasting blood glucose or 140-199 mg / dl of blood sugar for 2 hours of oral glucose tolerance test 4) After hearing and fully understanding the detailed description of this human study, the person who voluntarily decides to participate and agrees to follow the instructions.
Exclusion criteria
Exclusion criteria: 1) Those who have taken drugs that may affect blood glucose, such as hypoglycemic agents, diabetes treatments, obesity treatments, and lipid lowering agents, within 3 months from the screening test date 2) Patients diagnosed with type 1 or type 2 diabetes 3) have or suspected hereditary hyperlipidemia 4) Those with fasting triglyceride levels of 200 mg / dl or more at the screening test 5) Person who has clinically significant acute or chronic cardiocerebrovascular system, endocrine system, immune system, respiratory system, hepatobiliary system, kidney and urinary system, neuropsychiatric system, musculoskeletal system, inflammatory and blood, neoplastic, gastrointestinal diseases, etc. 6) Gastrointestinal disorders that may affect the absorption of human trial food or anyone with a history of gastrointestinal surgery (except for simple appendectomy or hernia surgery) 7) Person who shows the following result in laboratory examination ? AST, ALT> 3 times upper limit of normal range ? Serum creatinine> 2.0 mg / dl 8) Patients with systolic blood pressure of 160 mmHg or diastolic blood pressure of 100 mmHg or more (but those who are stably controlling blood pressure through medication can participate) 9) Persons with a history of hypersensitivity or clinically significant hypersensitivity reactions to human trial food 10) Those who have continuously taken dietary supplements (L-arabinose, guava leaf extract, etc.) or dietary supplements that may affect the results of this study within 2 weeks prior to the screening test 11) Participants in other clinical trials within 3 months before the screening test 12) have or suspect a history of alcoholism or drug abuse 13) A person deemed unsuitable for participation in a clinical trial due to laboratory test results or other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood glucose index(blood glucose level, AUC, Cmax, tmax, glycemic index);triglyceride index( triglyceride level, AUC, Cmax, tmax);insulin index( insulin level, AUC, Cmax, tmax, HOMA-IR, QUICKI, HOMA-ß);Visual analogue scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Antropometric(Height, weight, body mass index);vital sign(systolic/diastolic blood pressure, pulse);laboratory test ;Physical activity survey;Diet intake survey | — |
Countries
Korea, Republic of
Contacts
Public ContactSo Jang
Chonbuk National University
Outcome results
None listed