None listed
Conditions
Interventions
Medical Device : VUNO Med - DeepBrain AD software tells
Alzheimer's disease probability from uploaded images
Sponsors
Vuno
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Adults over 50 years old who visited the hospital between Jan 2010 and Sep 2019 and took brain magnetic resonance imaging (T1 weighted MRI) 2) Those who are classified as Disease group or Normal group according to the following criteria - Disease group: Amyloid PET positive, and who is diagnosed with probable/possible Alzheimer's disease (AD) according to NINCDS-ADRDA criteria, or with mild cognitive impairment (MCI) according to IWG criteria on MCI - Normal group: Amyloid PET negative, and who 1) does not appeal subjective cognitive decline or 2) has no objective cognitive decline
Exclusion criteria
Exclusion criteria: 1) Patients with dementia due to other causes than Alzheimer's disease 2) Cerebral lesions that may cause cognitive deficits (e.g., space-occupying lesions, subdural lesions, or normal cerebral pressure hydrocephalus, etc.) on brain T1-weighted MR images, or severe white matter hyperintensities (grade 3 or higher) on T2 FLAIR MR images 3) The interval between the date of diagnosis (or clinical evaluation) and the date of MRI is more than one year (only for Normal group and MCI patients in Disease group) 4) A person who is considered difficult to participate in this trial, as determined by the investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity | — |
Secondary
| Measure | Time frame |
|---|---|
| Area under the receiver operating characteristic curve | — |
Countries
Korea, Republic of
Contacts
Public ContactJong Bin Bae
Seoul National University Bundang Hospital
Outcome results
None listed