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A retrospective study to evaluate efficacy difference between combination therapies in the treatment of hypertensive patients with comorbidity.

A retrospective study to evaluate efficacy difference between combination therapies in the treatment of hypertensive patients with comorbidity.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0004746
Enrollment
106886
Registered
2020-02-19
Start date
2020-02-28
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Dongwha Pharmaceutical
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ? All patients diagnosed with essential (primary) hypertension as major or sub disease whose first diagnosis date was recorded from January 1, 2014 to December 31, 2018. ? Patients with heart failure, sleep apnea, menopause, obesity, dyslipidemia, type 2 diabetes before or after diagnosis of hypertension ? Patients with prescription record of ARB+CCB or ARB+HCTZ-based combinations ? Patients with a record of at least 4 weeks of prescription for the combinations and with confirmed daily dose ? Patients who underwent BP measurement within +/- 7 days of the prescription date based on the start and end of prescription of the combinations

Exclusion criteria

Exclusion criteria: Patients who do not meet the inclusion criteria are excluded.

Design outcomes

Primary

MeasureTime frame
A change in blood pressure measured from baseline

Secondary

MeasureTime frame
Blood pressure response rate (DBP; < 90mmHg or reduction of = 10mmHg, SBP; < 140mmHg or reduction of = 20mmHg);Goal rate (Combined SBP/DBP <140/90 mmHg and <130/80 mmHg in patients with diabetes mellitus and renal disease, respectively);Changes in metabolic risk (e.g. glucose, HbA1c, TC, LDL-C, HDL-C, TG);new onset of metabolic syndrome, including diabetes (NODM)

Countries

Korea, Republic of

Contacts

Public ContactHeesang Eum

Yonsei University Health System, Severance Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026