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Effectiveness of cooled radiofrequency ablation of genicular nerve in patients with chronic knee osteoarthritic pain: a double blinded randomized, sham-controlled study

Effectiveness of cooled radiofrequency ablation of genicular nerve in patients with chronic knee osteoarthritic pain: a double blinded randomized, sham-controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0004732
Enrollment
40
Registered
2020-02-12
Start date
2023-01-02
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : For both groups, the same high-frequency generator is used. 1) In the water cooled RF group, using a water cooled RF cannula that contains a circuit that can circulate physiologica

Sponsors

Asan Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Kellgren-Lawlence Grade II-IV on radiography with knee pain more than 6 months 2) Adult male and female patients aged 50 to under 80. 3) Patients who do not respond to treatment such as physiotherapy or drug therapy. 4) Patients with a numerical rating scale of 6 or higher 4) Pain reduction of more than 50% for more than 24 hours after 2cc injection of local anesthetic to the genicular nerve under c-arm guidance 5) Patients who have voluntarily agreed to participate in this clinical trial.

Exclusion criteria

Exclusion criteria: 1) Patients with acute knee pain (less than 6 months) 2) Patients who had previously had knee surgery 3) Patients with connective tissue disease that can cause knee pain (eg rheumatoid arthritis) 4) Patients with knee pain due to sciatica 5) Patients with side effects from local anesthetics or steroids 6) Patients who received steroid-containing treatment within the last 3 months 7) Patients with neurological or psychiatric problems 8) Patients who are contraindicated in nerve block such as blood clotting disorder or infection 9) If the patient does not agree to participate in the study

Design outcomes

Primary

MeasureTime frame
Successful responder

Secondary

MeasureTime frame
Successful responder;Numerical rating scale;Global perceived effect;Western Ontario and McMaster Universities Arthritis Index;Medication Quantification Scale III;Patient Health Questionnaire-9 (PHQ-9); complications

Countries

Korea, Republic of

Contacts

Public ContactSeong-soo Choi

Asan Medical Center

choiss@amc.seoul.kr+82-2-3010-1538

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026