Comparison of pupillary reflex dilation under general anesthesia with different inhaled anesthetics

Comparison of pupillary reflex dilation to standardized noxious stimulus during sevoflurane and desflurane anesthesia: a prospective randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0004653

Enrollment

Registered

2020-01-28

Start date

2020-01-20

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(Apply tetanus on the ulnar nerve as a standardized noxious stimulus under general anesthesia using sevoflurane or desflurane.) : The general anesthesia will be maintained with sevoflurane or de

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Patients aged 20-55 undergoing general anesthesia - American Society of Anesthesiologist(ASA) physical status classification I, II

Exclusion criteria

Exclusion criteria: - If the patient does not agree with the study - If the patient has hypertension or diabetes mellitus - If the patient has eye diseases such as Horner syndrome and Sjogren's syndrome - If the patient takes medicine that can affect autonomic nerve and central nerve systems (i.e., anticholinergicss, beta blockers/agonists, alpha adrenergics, anti-depressants, anti anxiety agents, sleeping pills, opioids) - If the patient has chronic pain

Design outcomes

Primary

Measure	Time frame
Pupillary reflex dilation before and after standardized noxious stimulus	—

Secondary

Measure	Time frame
Change of blood pressure, heart rate, and BIS (bispectral index) before and after standardized noxious stimulus	—

Countries

Korea, Republic of

Contacts

Public ContactSoo Yeon Kim

Hanyang University Seoul Hospital

Outcome results