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Short-term efficacy and safety of low-dose ticagrelor in acute coronary syndrome patients with high bleeding risk

Short-term efficacy and safety of low-dose ticagrelor in acute coronary syndrome patients with high bleeding risk

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CRIS
Registry ID
KCT0004640
Enrollment
126
Registered
2020-01-22
Start date
2017-05-08
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : This study is to compare the bleeding frequency of the 90 mg ticagrelor bid group and the 45 mg ticagrelor bid group after evaluating the degree of platelet inhibition in patients with acute co

Sponsors

Pusan National University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Acute Coronary Syndrome Patients who have completed a successful cardiovascular perfusion procedure PRU <90 patients Patients who voluntarily signed a research agreement

Exclusion criteria

Exclusion criteria: 1. Patients unable to take ticagrelor (severe chronic obstructive pulmonary disease, history of cerebral hemorrhage) 2. Patients with multi-vascular disease and coronary artery bypass surgery 3. Moderate-Those with severe liver disease 4. Those who have bradycardia symptoms such as same-sex bradycardia and atrioventricular conduction block 5. Those with respiratory distress, such as those with chronic obstructive pulmonary disease. 6. Pregnant or lactating women 7. Those who have undergone hemodialysis or peritoneal dialysis due to end stage renal failure and have undergone kidney transplantation 8. A person who, due to other reasons, judges that participation in a clinical trial is inappropriate.

Design outcomes

Primary

MeasureTime frame
BARC bleeding

Secondary

MeasureTime frame
platelet reactivity unit by VerifyNow;Borg Dyspnea scale;MACCE(CV death, MI, stroke), major bleeding

Countries

Korea, Republic of

Contacts

Public ContactJinsup Park

Pusan National University Hospital

dr.jinsup@gmail.com+82-51-240-7944

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 15, 2026