None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Elderly over 60 years old who can read and write text. 2.Diagnostic Criteria - The scores of K-MMSE are over 1.5 SD compared to the age, sex and education matched norm - In the neuropsychological tests, the scores of verbal / visual memory are normal compared to age / education matched norm (>16%ile)
Exclusion criteria
Exclusion criteria: 1. The elderly who have current or past major physical, neurological, or psychiatric disorders on history taking, physical examination, and laboratory test. 2. Those who have significant medical problems such as cancer. 3. Those who have significant neurological diseases that are required to be treated such as ischemic and hemorrhagic cerebral infarction. 4. Those who cannot read or write because of no education or illiteracy. 5. Those who are not applicable to perform the MRI scan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cortical thickness;variation in resting fMRI | — |
Secondary
| Measure | Time frame |
|---|---|
| Cambridge Neuropsychological Test Automated Battery (CANTAB);Korean version of Perceived Stress Scale, The Stress-symptom scale;Korean version of Geriatric Depression Scale;Korean version of Geriatric Depression Scale;Korean version of Pittuburgh Sleep Quality Index;Korean version of International Physical Activity Questionnaire;Positive Affect and Negative Scale | — |
Countries
Korea, Republic of
Contacts
Ewha Womans University