A study of pharmacokinetics and pharmacodynamics of dexmedetomidine in elderly patients

Evaluation of electroencephalogram pattern and pharmacokinetics and pharmacodynamics of dexmedetomidine in elderly patients during conscious sedation under spinal anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0004620

Enrollment

Registered

2020-01-09

Start date

2020-01-15

Completion date

Unknown

Last updated

2020-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Dexmedetomidine is permanently settled during surgery to a patient undergoing regular surgery under spinal anesthesia who wishes to sedate during surgery. The subjects were randomly assigned to

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing regular surgery under spinal anesthesia who wish to sedate during surgery Patients 65 years old to 85 years old American Society of Anesthesiologists Class 1, 2, 3

Exclusion criteria

Exclusion criteria: Those who are expected to have difficulty maintaining airway when sedated Have difficulty communicating Patients with cerebral nervous system diseases, including epilepsy Those who have neuropsychiatric disorders or take neuropsychiatric medications Have uncontrolled high blood pressure or heart disease Patients with renal impairment above CKD stage 4 BMI less than 18.5 kg/m2 or more than 30 kg/m2

Design outcomes

Primary

Measure	Time frame
Pharmacokinetics and pharmacodynamics of dexmedetomidine	—

Countries

Korea, Republic of

Contacts

Public ContactSeunghee Ki

Inje University Busan Paik Hospital

Outcome results