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Comparison of activity levels of cytokine in serum of patient with pancreatic cancer and validation of clinical effects

Comparison of activity levels of cytokine in serum of patient with pancreatic cancer, patient with other cancers (cholangiocarcinoma, stomach cancer, liver cancer, colorectal cancer, lung cancer), high risk for pancreatic cancer and benign pancreatic disease and healthy control and validation of clinical effects, pilot study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0004614
Enrollment
510
Registered
2020-01-08
Start date
2018-11-16
Completion date
Unknown
Last updated
2020-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Yonsei University Health System, Gangnam Severance Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Pancreatic cancer 1). Patients with pancreatic cancer confirmed by imaging (CT, MRI, PET-CT) 2). Patients with pancreatic cancer diagnosed using cytology by endoscopic ultrasound 3). Patients who underwent surgical treatment with pancreatic cancer 2. Patients with other carcinomas (biliary cancer, stomach cancer, liver cancer, colon cancer, lung cancer) 1) Biliary cancer: Patients suspected of biliary tract cancer by imaging tests (CT, MRI, PET-CT) and biliary endoscopic examination and confirmed biliary tract cancer by tissue or cytology examination 2) Stomach cancer: Patients suspected of stomach cancer by imaging tests (CT, MRI, PET-CT) and endoscopic examination and confirmed stomach cancer by tissue or cytology examination 3) Liver cancer: Patients suspected of liver cancer by imaging tests (CT, MRI, PET-CT) and confirmed liver cancer by tissue or cytology examination 4) Colorectal cancer: Patients with colorectal cancer suspected by imaging tests (CT, MRI, PET-CT), and colonoscopy and confirmed colorectal cancer by tissue or cytology examination 5) Lung cancer: Patients whose lung cancer is suspected by imaging tests by imaging tests (X-ray, CT, MRI, PET-CT), sputum cell test, and bronchoscope and confirmed lung cancer by tissue or cytology examination 3. Patients with high risk for pancreatic cancer Patient diagnosed with ? chronic pancreatitis ? pancreatic cyst ? benign pancreatic mass ? pancreatic duct dilatation by imaging studies (US, CT, MRI) ? Patients diagnosed with diabetes within two years of age 55 and older ? Patients with elevated CA 19-9 levels (50U / mL or higher; normal reference value: 0.8-24 U / mL) 4. Patients with benign pancreatic disease Patient diagnosed with acute pancreatitis 5. healthy control Those who have not been diagnosed with malignant or pancreatic diseases through a medical examination within 6 months of the decision to participate in the study

Exclusion criteria

Exclusion criteria: 1. Minors under the age of 19, vulnerable subjects such as illiteracy 2. Those who have received immunosuppressive drugs from past medical history

Design outcomes

Primary

MeasureTime frame
Comparative evaluation of cytokine expression in serum of pancreatic cancer patients, other carcinomas (biliary cancer, gastric cancer, liver cancer, colon cancer, lung cancer), patients with high risk of pancreatic cancer, patients with benign pancreatic disease and normal subjects

Secondary

MeasureTime frame
Evaluation of cytokine expression as a factor predicting pancreatic cancer diagnosis and prognosis

Countries

Korea, Republic of

Contacts

Public ContactSung Ill Jang

Yonsei University Health System, Gangnam Severance Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 11, 2026