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Recurrence free survival after hepatectomy using propofol-based anesthesia and sevoflurane-based anesthesia: a randomized controlled study

Recurrence free survival after hepatectomy using propofol-based anesthesia and sevoflurane-based anesthesia: a randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0004599
Enrollment
536
Registered
2020-01-03
Start date
2020-01-07
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Sponsors

Samsung Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: -Adults who undergo elective hepatectomy for hepatocellular carcinoma (older than 18 years old and younger than 76 years old) -American society of anesthesia (ASA) class I-III -Patients who have agreed to the trial and signed the subject's consent

Exclusion criteria

Exclusion criteria: - Patients with who have history of side effects from the use of the anesthetic or have contraindication for drugs (a patient suspected of having an allergic reaction to the drug) - Patients who have liver cancer other than hepatocellular carcinoma (eg Cholangiocarcinoma or metastatic liver tumor) - Patients who is deemed inappropriate to participate in the clinical trial by the researcher's judgment - Patients who are allergic to nuts or beans - Patients who have a history of malignant hyperthermia or risk factors of malignant hyperthermia - Patients who underwent interventional procedure for HCC - Patients who have elevated intracranial hypertension - Patients who have distant metastasis to other organ - Patients who undergo ALPS (Associating liver partition and portal vein ligation for staged hepatectomy)

Design outcomes

Primary

MeasureTime frame
1 year recurrence free survival

Secondary

MeasureTime frame
1 year overall recurrence;1 year overall metastasis;1 year overall survival;3 year recurrence free survival;3 year overall survival;3 year recurrence;3 year metastasis

Countries

Korea, Republic of

Contacts

Public ContactJi-Hye Kwon

Samsung Medical Center

kwonjh0828@hanmail.net+82-2-3410-0369

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Jul 23, 2026