Effect of chronic alcohol consumption on Dose of dexmedetomidine for inducing sedation during spinal anesthesia

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0004561

Enrollment

Registered

2019-12-18

Start date

2019-12-23

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : 1. Load 1mcg/kg of dexmedetomidine with intravenous injection over 20 minutes and assess the patient&#39

s sedation level. 2. The patient&#39

s target sedation level is set at BIS 70, and this study&#39

s goal is to assess the required amount of dexmedetomidine needed to achieve BIS 70. 3. Record the BIS and OAA/S of 10 minutes, 15 minutes, and 20 minutes since Dxmedetomyidine loading. If there are a

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who are scheduled to undergo elective surgery 2. Patients of the American Society for the Classification of Physical Levels (ASA PS) 1-3 3. Patients aged 19 to 70 4. Patients voluntarily agreed to participate in this clinical trial in writing

Exclusion criteria

Exclusion criteria: 1. Patient with any contraindication to regional anesthesia. 2. Pregnant women 3. Patient with central nervous system acting medication 4. Patient with severe pain now 5. Patient with apparent liver disease or kidney disease 6. Patients with diseases including cardiovascular, respiratory, and nervous system 6.1 Patients with ECG abnormality and amiodarone in use 6.2 bradycardia (less than 50 heartbeats) 7. High spianl block of T4 or higher or conversion to general anesthesia 8. Patients deemed unfit for other studies

Design outcomes

Primary

Measure	Time frame
Amount of dexmedetomidine required to be BIS 70 between NHD and HD Group	—

Secondary

Measure	Time frame
Rescue midazolam requirement;Incidence of paradoxical rexcitement response;Incidence of side effects associated with dexmedetomidine or midazolam	—

Countries

Korea, Republic of

Contacts

Public ContactSu Yeong Cho

Chonnam National University Hospital

Outcome results