Development of Mealbox for Relieving Oxidative Stress in Korean Elderly with Metabolic Syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0004549

Enrollment

Registered

2019-12-12

Start date

2018-03-12

Completion date

Unknown

Last updated

2019-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : For experimental group, 3 meal boxes were delivered to their home every day. The food in the meal boxes were made from ingredients with high antioxidant capacity. ORAC value was u

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The subjects who met 3 or more items of IDF criteria for metabolic syndrome were enrolled. The criteria for IDF are as follows, waist circumference (male > 90cm, Female > 80cm), serum fasting plasma glucose > 100mg/dL, serum triglyceride > 150mg/dL, serum HDL-cholesterol (male < 40mg/dL, Female < 50 mg/dL), systolic blood pressure (SBP) > 130mmHg or diastolic blood pressure (DBP) > 85mmHg.

Exclusion criteria

Exclusion criteria: current smoker current drinker of at leasr 1 glass a day (355ml beer, 5oz wine 1.3 glass of soju) a person who have gained or lost 5% or more of their total weight in the last month a person who is allergic or hypersensitive reaction to certain foods a person who are mentally ill or who don't understand the purpose and method of study, suchas those who are addicted to drugs or alcohol a person who cannot read consent forms, such as illiteracy or foreigners a person who do not want to participate in study or refuse to fill up consent forms.

Design outcomes

Primary

Measure	Time frame
waist circumference;Blood pressure (systolic and diastolic);Lipid profile (total cholesterol, triglyceride, HDL & LDL cholesterol);Fasting plasma glucose (fasting 8-hours);oxygen radical absorbance capacity (ORAC);Advanced Glycation End products (AGEs)	—

Secondary

Measure	Time frame
Serum C-peptide;Serum insulin;Apolipoprotein B;Body mass index (BMI);Protein carboxylation;Lipid peroxidation;Oxidized LDL;tumor necrosis factor - alpha;small dense LDL;Pulse wave velocity (PWV);Glycated hemoglobin (HbA1c);Fat measured Computed Tomography (CT)	—

Countries

Korea, Republic of

Contacts

Public ContactJung Hye Kim

Yonsei University Health System, Gangnam Severance Hospital

Outcome results