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A randomized control trial comparing the efficacy of ramosetron versus ondansetron for pain control and management of postoperative emesis after arthroscopy rotator cuff repair

Prevalence and prevention of postoperative nausea and vomiting in patients after arthroscopic rotator cuff repair

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CRIS
Registry ID
KCT0004460
Enrollment
120
Registered
2019-11-22
Start date
2011-09-01
Completion date
Unknown
Last updated
2019-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Experimental groups of prophylaxis, designated by randomization, were injected intravenously with ramosetron 0.3 mg or ondansetron 4 mg, respectively, immediately after surgery, and one more do

Sponsors

The Catholic University of Korea, Seoul St. Mary's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The criteria for the selection: Voluntary agreement, since September 2011, among patients diagnosed as rotator cuff tear by single orthopedic surgeon at the Catholic University of Korea St. Mary's Hospital, plus those who are needed to undergo arthroscopic rotator cuff surgery and 20 years old or older patients.

Exclusion criteria

Exclusion criteria: The exclusion criteria were as follows: (a) previous surgery, (b) trauma history, (c) intolerance or allergy to any drugs used in the study, (d) severe bowel motility impairment, (e) administration of another antiemetic drug 24 h before surgery, (f) alcohol or opioid dependence, (g) history of cardiovascular or respiratory disease, and (h) renal or hepatic functional impairments. In addition, we excluded patients when general anesthesia was contraindicated.

Design outcomes

Secondary

MeasureTime frame
paint at the operative site

Primary

MeasureTime frame
Nausea and vomiting

Countries

Korea, Republic of

Contacts

Public ContactHyo Lee

The Catholic University of Korea, Seoul St. Mary's Hospital

hyojin1229@gmail.com+82-2-2258-1511

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026