None listed
Conditions
Sponsors
P&K Skin Research Center
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Women over 40 years old and under 55 years old 2) In a visual evaluation, both left and right eye wrinkles are grade 3 or higher 3) Using Corneometer®, measure the amount of water in both cheeks. Left and right cheeks are less than 49AU 4) Those who have agreed to participate in this test prior to the start of the test and have signed a written consent form
Exclusion criteria
Exclusion criteria: 1) Those who have or are currently undergoing treatment for skin diseases such as atopic dermatitis and psoriasis 2) Sensitive or allergic to food ingredients for this human application test 3) People with abnormal skin conditions such as spots, acne, erythema, and capillary dilation in the test area 4) Visit 1 A person who received treatment on the facial (skin stripping, other skin care, etc.) or received treatment on the facial area within 6 months 5) Visitor 1 Use a skin external substance containing steroids on the facial part or take an oral retinoid/steroid agent within 3 months of the standard visit 6) Visitor 1 Use functional cosmetic (retinoid agent, retinol, AHA) or moisturizing cosmetic or skin care (LED mask, ion booster, etc.) to improve wrinkles within 2 weeks of visit 7) People who take diet pills (absorbent and antidepressants, appetite suppressants, etc.) and contraceptives or hormones or diuretics within one month based on visit1 8) Visitors who have taken antioxidants, hyaluronic acid, health function foods containing collagen, moon flower species freedom, vitamin A, vitamin C, vitamin E-containing medicines and health function foods within two weeks of visit1; 9) Visit 1 A person who has participated in other interventional clinical tests (including human application tests) within one month of the standard or plans to participate in other interventional clinical tests (including human application tests) after the start of this human application test. 10) Person whose AST (GOT) or ALT (GPT) is 120IU/L or higher, or whose ?-GTP is 180IU/L or higher 11) Those whose creatine is 2.4 mg/dl or higher 12) A person who is less than or equal to 0.1µIU/ml of TSH or greater than 10µIU/ml of TSH 13) Unregulated hypertension patients (based on measurement after 10 minutes of stabilization, at least 160mmHg of the hydraulic pressure or more than 100mmHg of the relaxant blood pressure) 14) Unregulated diabetics (more than 180 mg/dl per empty blood) 15) People with schizophrenia, depression, drug addiction, etc. 16) Those who are pregnant, nursing, or planning to conceive within three months; 17) Those who are in hospital, drug treatment, and rehabilitation for alcohol use ·Distribution disorder, heart disease, and central nervous disorder 18) Smokers or those who smoke less than a year after quitting smoking 19) A person who judges that the tester is inappropriate for this test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| skin folds;skin moisture content | — |
Secondary
| Measure | Time frame |
|---|---|
| Transepidermal Water Loss;the thick skin Water Quantity;skin elasticity;Eye wrinkle volume;Evaluation of improvement for testers and human application test takers | — |
Countries
Korea, Republic of
Contacts
Public ContactHae Lee
P&K Skin Research Center
Outcome results
None listed