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The comparative study of 7 and 14 days bismuth-containing quadruple therapy as first line therapy for eradication of clarithromycin-resistant Helicobacter pylori

Bismuth Containing Quadruple First Line Therapies for Eradication of Clarithromycin-Resistant Helicobacter pylori : Comparison of Eradication rate of 7 and 14 days Treatment duration

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CRIS
Registry ID
KCT0004414
Enrollment
162
Registered
2019-11-01
Start date
2020-03-12
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Each researcher conducts 7 or 14 days quadruple therapy with ilaprazole, bismuth, metronidazole, and tetracycline to their patient who has a peptic ulcer including scars and clarithromycin-resi

Sponsors

The Catholic University of Korea, Eunpyeong St. Mary's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Patients over 19 year and below 75 year - Patients with clarithromycin-resistant H. pylori-positive according to results of Dual Priming Oligonucleotide-Based Multiplex Polymerase Chain Reaction and biopsy - Patients who agree to participate in this clinical trial and sign voluntarily - Patients who don’t have dementia or cognitive impairment

Exclusion criteria

Exclusion criteria: - Those with the history of administration with other antibiotic within 1 month. - The highly sensitive person to experimental drug - Those who has undergone upper gastrointestinal surgery - Those who take anticoagulant or steroids - Liver disorder or renal disorder patients - Pregnant or lactating women or childbearing women suspected pregnant - Alcohol addictor or those with the history of drug abuse - Those who participated in other clinical trial within 6 months before this clinical trial - Those who are judged to be improper for this clinical trial

Design outcomes

Primary

MeasureTime frame
Urea breath test

Secondary

MeasureTime frame
Adverse events

Countries

Korea, Republic of

Contacts

Public ContactChulhyun Lim

The Catholic University of Korea, Eunpyeong St. Mary's Hospital

diluck1@naver.com+82-2-2030-4316

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026