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A Study on the Change of Drug Capacity and Brain Wave in Dental Treatment under Patient-Controlled Sedation Using Dexmedetomidine

A Study on the Change of Drug Capacity and Brain Wave in Dental Treatment under Patient-Controlled Sedation Using Dexmedetomidine

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CRIS
Registry ID
KCT0004359
Enrollment
30
Registered
2019-10-21
Start date
2019-10-07
Completion date
Unknown
Last updated
2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Use 4µg/ml diluted with 50ml of dexmedetomidine using saline solution in a syringe of 200 µg/2 ml Vial 50cc in Perfusor Space(B.Braun Mesungen AG, Germany). There is no initial loading dose and
previous paper, it was confirmed that the patient was properly sedated when 0.1 mcg/kg was conducted. In this study, 0.2 mcg will be administered from high-capacity and 0.05 mcg from low-capacity. Ac
s study, 70.2&#37
remained sedated when 2 mcg/kg was administered as a bolus and continued for 10 minutes at a concentration of 1 mcg/kg/h, while the remaining 29.8&#37
were diagnosed with the second dose of the bolus. Most of the readings are taken in the first 10 minutes of administration of 2-3 mcg/kg. In addition, patient-controlled sedation is less likely to be

Sponsors

Seoul National University Dental Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.American Society of Anesthesiologists(ASA) level 1 to 2 subjects who receive scaling treatment at Seoul National University Medical Center 2. Adults aged 20 years and under 60 years 3. Patients who have been briefed and agreed in writing

Exclusion criteria

Exclusion criteria: 1. Subject to American Society of Anesthesiologists(ASA) Level 3 or 4 2. Subjects under the age of 20 3. In case of cardiovascular or respiratory history; 4. Subjects with substrate diseases of the brain, such as cerebrovascular diseases and brain tumors 5. In case of mental illness such as mental retardation and autism 6. Subjects who are difficult or expected to maintain prayers 7. Pregnant woman 8. Subjects who disagreed with the study

Design outcomes

Primary

MeasureTime frame
The vital signs( blood pressure, pulse rate, carbon dioxide pressure, and pulse oxides, etc) of a patient during the implementation of sedation;Patient's state of consciousness and EEG during the implementation of sedation;Patient's reaction during the implementation of sedation;Evaluate the patient's recovery and satisfaction after the sedation is implemented;Total sedative implementation time, the number of times the patient pressed the demand button, and the amount of medication injected

Secondary

MeasureTime frame
Evaluation of the Satisfaction of the Surgeon in Skelling under sedation

Countries

Korea, Republic of

Contacts

Public ContactRhee Hyun

Seoul National University Dental Hospital

omsrheesh@gmail.com+82-2-2072-3847

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026