None listed
Conditions
Interventions
Others : Group A: Start Bazedoxifene acetate within 2 days after open reduction and internal fixation for distal radius fracture
Group B: Start Bazedoxifene acetate at postoperative 3 months after ope
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) AO/OTA classification A2, A3, B3, C1, C2, C3 distal radius fracture patients who agree to have operative treatment 2) Osteopenia or osteoporosis patients who had T-score -1.0 or under than -1.0 3) More than two years after menopause
Exclusion criteria
Exclusion criteria: 1) History of parathyroid treatment 2) History of medication which influence on the osteoclast such as Denosumab within 6 months 3) History of Bisphosphonate within 2 years 4) History of distal radius fracture in the same upper extremity 5) Pathologic fracture patients 6) GFR under 35 7) Patients who had hypocalcemia or swallowing difficulty 8) Patients who need to have long term bed rest or who has a history of deep vein thrombosis 9) Patients who had idiopathic uterine bleeding or symptoms of endometrial cancer and patients who had drug sensitivity to Bazedoxifene acetate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fracture healing time | — |
Secondary
| Measure | Time frame |
|---|---|
| functional recovery after fracture | — |
Countries
Korea, Republic of
Contacts
Public ContactYoung Ho Shin
Asan Medical Center
Outcome results
None listed