A randomized clinical trial comparing intrathecal morphine and continuous erector spinae block for postoperative analgesia in living donors for liver transplantation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0004313

Enrollment

Registered

2019-10-15

Start date

2019-10-15

Completion date

Unknown

Last updated

2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : Patients are randomly allocated to the 2 groups: a continuous bilateral erector spinae plane block group and an intrathecal morphine group.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult (=19 years old or >19 years old) American society of anesthesiologist physical status I, II: healthy (I), controlled systemic disease (II)

Exclusion criteria

Exclusion criteria: American society of anesthesiologist physical status higher than III: uncontrolled systemic disease (III), severe systemic disease (IV), death (V) Child ( 70 years old) Pregnancy Coagulopathy Unstable coronary artery disease, congestive heart failure, arrythmia, cardiomyopathy Cerebrovascular disease Systemic infection, infection at site of erector spinae plane block chronic pain disorder Refusal to study Allergy to local anesthetics Psychiatric disease

Design outcomes

Primary

Measure	Time frame
cumulative opioid consumption at 48 hours postoperatively	—

Secondary

Measure	Time frame
pain scores;cumulative opioid consumption;patient satisfaction with pain relief;quality of sleep;quality of recovery;catheter-related complications (disruption, infection, leakage, migration);Time to first flattus;Time to first ambulation;postoperative nausea, vomiting, and pruritus;incidence of respiratory depression and post-dural puncture headache;intraoperative remifentanyl consumption and surgical pleth index;block performance time;block failure rate;pain characteristics and duration	—

Measure

Time frame

pain scores;cumulative opioid consumption;patient satisfaction with pain relief;quality of sleep;quality of recovery;catheter-related complications (disruption, infection, leakage, migration);Time to first flattus;Time to first ambulation;postoperative nausea, vomiting, and pruritus;incidence of respiratory depression and post-dural puncture headache;intraoperative remifentanyl consumption and surgical pleth index;block performance time;block failure rate;pain characteristics and duration

—

Countries

Korea, Republic of

Contacts

Public ContactRyungA Kang

Samsung Medical Center

Outcome results