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A Randomized, Double-blinded, Placebo-controlled, Multi-center Phase 2 Study to Explore the Efficacy and Safety of Subcutaneous Injection EG-Myocin Immediately Before and After PCI in Patients with Acute ST-Elevation Myocardial Infarction (STEMI)

A Randomized, Double-blinded, Placebo-controlled, Multi-center Phase 2 Study to Explore the Efficacy and Safety of Subcutaneous Injection EG-Myocin Immediately Before and After PCI in Patients with Acute ST-Elevation Myocardial Infarction (STEMI)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CRIS
Registry ID
KCT0004288
Enrollment
60
Registered
2019-09-09
Start date
2019-12-24
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : 1. Investigational Product(EG-Myocin) 2. Placebo(EG-Myocin ??)

Sponsors

Eyegene
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Ability to provide informed consent - Male : 19 ~ 75 years, Female : 50 ~ 75 years - ST-segment elevation myocardial infarction - PPCI - Able to consent for blood draw

Exclusion criteria

Exclusion criteria: - Left main coronary artery - Cardiac arrest or arrhythmia where CPR or unscheduled circulatory aids have been used during diagnosis - Cardiac shock - uncontrolled hypertension - CABG, coronary artery bypass graft - An arrhythmia patient who has clinically significant - Severe renal disorders - Severe liver disorders - Medical history of malignant carcinoma within past 3 years - Subjects who have hypersensitivity reaction anamnesis for components of Investigational Product. - Treatment with other investigational agents or devices within the previous 30 days, planned use of investigational drugs or devices, or previous enrolment in this trial

Design outcomes

Primary

MeasureTime frame
Inhibitory Effect of Investigational Medicinal Product on Myocardial Ischemia / Reperfusion Injury

Secondary

MeasureTime frame
Effect of Investigational Medicinal Product on Physiological Status of Myocardial Infarction

Countries

Korea, Republic of

Contacts

Public ContactChul-Min Ahn

Yonsei University Health System, Severance Hospital

drcello@yuhs.ac+82-2-395-9457

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026