FindTrial
Sign In

Comparison of brain perfusion in rhythm control and rate control of persistent atrial fibrillation: Prospective randomized trial

Comparison of brain perfusion in rhythm control and rate control of persistent atrial fibrillation: Prospective randomized trial

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0004262
Enrollment
200
Registered
2019-08-30
Start date
2017-10-23
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Yonsei University Health System, Severance Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: •Patients who recurred after DC cardioversion, and •Patients with persistent Atrial fibrillation (20~80 Years old), and •LA diameter < 55mm, and •patients possible to anticoagulation and anti arrhythmic drug

Exclusion criteria

Exclusion criteria: 1. Atrial fibrillation accompanied by severe cardiac deformities or hemodynamic effects of structural heart disease 2. Patients with severe new function disorder or CT imaging with contrast medium difficult 3.An additional cerebral perfusion CT examination due to repeated radiation exposure is inappropriate 4.Past atrial fibrillation High Frequency Electrodelectomy or maze surgery patients with past history 5. Patients with active internal bleeding 6.Adaptive therapy and anticoagulant insufficiency 7.Flammatic atrial fibrillation (Grade 2, Mechanical valve, mitral valve cosmetic surgery) 8. Cardiac blood rate < 30% 9.Cerring serious co-morbidities of the symptom 10. Patients with an expected survival period of less than one year 11.Patients who are addicted to drugs or alcohol 12.Patients judged by other researchers to be unfit to participate in a clinical trial

Design outcomes

Primary

MeasureTime frame
Cognitive function changes (K-MOCA:Korea-Montreal Cognitive Assessment) and cerebral perfusion CT (Brain perfusion CT)—

Secondary

MeasureTime frame
Composite events: all cause mortality, hospitalization rate, stroke rate, heart failure rate, and major cardiovascular complications incidence rates;Comparison of actual rhythm control (On treat analysis);Comparison of incidence of side effects during antiarrhythmic or anticoagulant therapy;Comparison of Frequency and Complication Rate of High Frequency Electrode Ceramic Resection—

Countries

Korea, Republic of

Contacts

Public ContactKIM HOON

Yonsei University Health System, Severance Hospital

thkimcardio@yuhs.ac+82-2-228-8467

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026