Comparison of Synergistic Sedation With Midazolam and Propofol Versus Midazolam and Pethidine in Colonoscopies

Comparison of Synergistic Sedation With Midazolam and Propofol Versus Midazolam and Pethidine in Colonoscopies: A Prospective, Randomized Study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0004225

Enrollment

300

Registered

2019-08-21

Start date

2020-05-18

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : We will use midazolam and pethidine combination therapy (Group A) or midazolam and propofol combination therapy (Group B), which are commonly used as sedation endoscopic drugs. In the case of

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who want to sedative colonoscopy in Chonnam National University Hospital

Exclusion criteria

Exclusion criteria: A. Under 20 years old or over 75 years old B. Patients with poor general condition [patients with ASA grade (American Society of Anesthesiologists' Physical Status Classification) IV or higher] C. If insufficient colonoscopy is performed D. Patients with cirrhosis E. Patients undergoing dialysis F. Pregnant woman G. Patients who chronically used benzodiazepine or opioid drugs H. Patients weighting less than 45 kg or weighting more than 90 kg

Design outcomes

Primary

Measure	Time frame
blood pressure, bradycardia or tachycardia, decreased oxygen saturation, etc. Safety	—

Secondary

Measure	Time frame
Identify patient's pain, satisfaction, recovery time	—

Countries

Korea, Republic of

Contacts

Public ContactDong Hyun Kim

Chonnam National University Hospital

Outcome results