None listed
Conditions
Interventions
None listed
Sponsors
Bundang CHA General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All patients who were between 15 and 79 years old, with reflux symptoms, and scheduled to undergo a screening gastroscopy and EndoFLIP® were included in this study. According to the results, patients with erosive esophagitis, determined by gastroscopy, were referred to the ERD group, while patients with no erosive esophagitis, but with abnormalities observed over 24-hour pH monitoring were classified as the NERD group.12 Healthy controls were on no regular medications and had no symptoms of reflux disease, but did have nonspecific symptoms, such as dyspepsia or abdominal discomfort.
Exclusion criteria
Exclusion criteria: (1) unable to receive a gastroscopy or EndoFLIP®; (2) unable to provide informed consent; (3) hemodynamic instability (systolic blood pressure [SBP] < 90 mmHg), or if the peripheral oxygen saturation (SpO2) was 90% in room air, or < 95% on 2 L/min of oxygen at baseline before the procedure; (4) psychological problems; (5) acute severe infection; (6) evidence of esophageal motility disorder on esophageal manometry.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cross sectional area, distensiblity index | — |
Secondary
| Measure | Time frame |
|---|---|
| Residual LES pressure, 24-hr ambulatory pH monitoring | — |
Countries
Korea, Republic of
Contacts
Public ContactJoo Young Cho
Bundang CHA General Hospital
Outcome results
None listed