None listed
Conditions
Interventions
Drug : Low-dose statin / ezetimibe rosuvastatin 5mg + ezetimibe 10mg (CRETEJETE) is similar to rosuvastatin 20mg (high-dose statin monotherapy) in LDL-cholesterol-lowering therapy, but does not increa
Sponsors
Kyung Hee University Hosipital at Gangdong
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) patients over 20 years old with type 2 diabetes 2) Those who are under the control of blood glucose control by lifestyle therapy or metformin alone. 3) Diagnosis of diabetes less than 10 years 4) When registering HbA1c = 8.0% 5) LDL cholesterol = 70 mg / dl 6) Those who have agreed with the written consent of the subject for participation in clinical trials
Exclusion criteria
Exclusion criteria: 1) Those who took a lipid lowering agent for more than a week within the last 3 months 2) Those who took a lipid lowering agent for more than one day in the past month 3) Within 3 months, major cardiovascular disease 4) Those who are taking medication for weight loss or who are scheduled 5) Those who are taking or are planning to take drugs that affect the metabolism of sugar, such as systemic steroids 6) Serum AST, ALT Upper Normal Limit more than 2 times 7) Serum creatinine> 1.5 mg / dl 8) Untreated hyperthyroidism, hypothyroidism 9) Triglyceride = 500 mg / dl 10) Malignant tumor under treatment 11) Pregnancy 12) Any person deemed unable to participate in research under the judgment of the researcher
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare HbA1C changes | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of fasting blood sugar change;Comparison of insulin change;Comparison of glucagon change;Comparison of HOMA-B change;Comparison of insulinogenic index change;Comparison of disposition index change;Comparison of HOMA-IR change;Comparison of Matsuda index change;Comparison of Stumvoll index change;Comparison of OGIS index change;Comparison of LDL cholesterol change;Comparison of Non-HDL cholesterol change;Comparison of ApoB change;Comparison of ApoB/Apo-A1 change;Comparison of High-sensitivity CRP change | — |
Countries
Korea, Republic of
Contacts
Public Contactjunghwa lee
Kyung Hee University Hosipital at Gangdong
Outcome results
None listed