None listed
Conditions
Interventions
Procedure/Surgery : Adenomyosis debulking surgery (adenomyomectomy):
We designed a novel operative procedure consisting of the following methods. First, an initial measurement of the adenomyotic lesi
hence, the argon laser, rather than a scalpel, was used to peel off the adenomyotic tissue in a direction parallel to the endometrial plane. The entire adenomyotic lesion was not removed at once
rather, small amounts of the adenomyotic tissue, 2-3 mm thick, were shaved off with the argon laser several times. Throughout this step, the thickness of the residual myometrium was frequently measure
Sponsors
Dongguk University Ilsan Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with adenomyosis via pelvic ultrasonography and magnetic resonance imaging (MRI) who had excessive menstrual flow and severe dysmenorrhea that disrupted daily life 2. Patients who had been diagnosed with primary or secondary infertility for more than a year, and their infertility was determined to be because of adenomyosis based on clinical assessments by an infertility exper 3. Patients who did not have any other medical conditions, excluding iron deficiency anaemia 4. Patients who failed to conceive after treatment with drugs, such as gonadotropin-releasing hormone agonist (GnRHa) 5. Infertile patients who had adenomyosis and other infertility factors, such as ovulation disorder and blocked fallopian tube,yet their implantation failure was determined to be because of adenomyosis after more than two failed attempts to conceive through IVF-ET and/or ovulation induction
Exclusion criteria
Exclusion criteria: 1. Patients with gynecologic malignancies such as cervical cancer or ovarian cancer 2. Patients with severe medical disease 3. Patients with active bacterial infection which needs parenteral antibiotics treatment 4. Patients who received pelvic irradiation due to malignancies 5. Patients with other severe medical disease 6. Patients with psychologic disorder 7. Patients who is impossible to participate in clinical trial by the law
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregnancy and its outcome | — |
Secondary
| Measure | Time frame |
|---|---|
| Dysmenorrhea and menorrhagia | — |
Countries
Korea, Republic of
Contacts
Public ContactJu-Won Roh
Dongguk University Ilsan Hospital
Outcome results
None listed