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Comparative Analysis of Therapeutic Effect Between Theranova Dialyzer and High Flux Dialyzer Using OMICS

Comparative Analysis of Therapeutic Effect Between Theranova Dialyzer and High Flux Dialyzer Using OMICS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0004130
Enrollment
20
Registered
2019-07-09
Start date
2019-07-31
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : Dialysis schedule and time is implemented equally in each group. Every dialysis three times a week, four hours during each dialysis will be planned. Although blood flow could be adjus

Sponsors

Pusan National University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. A person who have maintained hemodialysis for more than three months due to end stage kidney disease and have not changed their drug use for the past mont 2. A person whose hemodialysis access is not a catheter, who can maintain a blood flow rate of more than 250 ml/min 3. A person who have been provided with a description of all matters relating to the study and voluntarily signed and dated prior to participating in the study.

Exclusion criteria

Exclusion criteria: 1. A person whose hemodialysis schedule is not three times per wee. 2. A person who peritoneal dialysis is also conducted with hemodialysis such as hybrid dialysis treatment. 3. A person receiving inpatient treatment to serious disease within the period studied. 4. A person who complain of a severe fluctuation of blood pressure and intractable fatigue during hemodialysis. 5. A person with frequent changes of dry weight and dialysis prescription 6. A persion who maintain dialysis with catheter 7. A person who can't measure blood pressure in upper arm. 8. A person with a malignant tumor history who has a symptom or who has not been diagnosed with a complete cure. 9. pregnant and breastfeeding targets 10. A person who participated in other clinical trials with interventional design. 11. A person who is not suitable for this study according to judgement of investigators 12. A person with vulnerable or limited ability to agree with this study

Design outcomes

Primary

MeasureTime frame
proteomics (blood, dialysate);metabolomics (blood, dialysate)

Secondary

MeasureTime frame
proteomics (dialysis membrane fiber);metabolomics (dialysis membrane fiber);clearance of middle molecules (a1-microglobulin, fetuin A, Fibroblast growth factor-23)

Countries

Korea, Republic of

Contacts

Public ContactHyo Jin Kim

Pusan National University Hospital

kimhj923@gmail.com+82-51-240-7204

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026