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Does The Epinephrine Require In Periarticular Injection Cocktail For Total Knee Arthroplasty?

Comparison of pain between the presence and the absence of epinephrine in periarticular injection after total knee arthroplasty -A prospective, randomized, double-blind trial -

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0004036
Enrollment
102
Registered
2019-06-05
Start date
2016-10-12
Completion date
Unknown
Last updated
2019-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : In the final stage of total knee arthroplasty, a mixture of triamcinolone(1ml), 0.5&#37
ropivacaine(20ml) iis devided into 14ml and 7ml fluid, and 14 ml fluid was mixed with normal saline to make 50 ml and injected around the posterior capsule, femoral attach of medial collateral ligamen
ropivacaine 20ml) before adding the saline Group N : only the mixture fluid(triamcinolone1ml + 0.5&#37
ropivacaine 20ml + normal saline) above is injected

Sponsors

Hanyang University Seoul Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who underwent primary total knee arthroplasty due to degenerative osteoarthritis

Exclusion criteria

Exclusion criteria: Patients aged 55 years or less, 85 years or more, preoperative American Society of Anesthesiologists score (ASA) of 4 or more, post-traumatic arthritis, secondary arthritis, patients who underwent bilateral total knee arthroplasty simultaneously were excluded.

Design outcomes

Primary

MeasureTime frame
Numerical rating scale(NRS) of pain

Secondary

MeasureTime frame
Cumulative dose of fentanyl;Range of motion of knee joint;Wound complication

Countries

Korea, Republic of

Contacts

Public ContactYoung Il Ko

Hanyang University Seoul Hospital

camilo0205@naver.com+82-2-2290-8486

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026