Can Preoperative Ferric Carboxymaltose Reduce Postoperative Blood Transfusion in Bilateral Total Knee Arthroplasty

Can Preoperative Ferric Carboxymaltose (FCM) Reduce Postoperative Blood Transfusion in Bilateral Total Knee Arthroplasty : Randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0004015

Enrollment

156

Registered

2019-05-30

Start date

2019-06-03

Completion date

Unknown

Last updated

2019-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : In study group, Ferric Carboxymaltose injection is done 2 weeks before surgery, continuously for 15~30 minutes. In control group, same amount of normal saline injection is done by the same meth

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who undertake bilateral staged Total Knee Arthroplasty, and havd iron deficiency anemia (Male 8<Hb<13, Female 7<Hb<13)

Exclusion criteria

Exclusion criteria: - First operation Preop Hb <8g/dL, thrombocytopenia - C-reactive protein 1 or more (> 2xUNL) - Systemic inflammatory diseases - Use of iron supplements within 4 weeks - Intravenous iron, or erythropoietin within 4 weeks - Preoperative use of anticoagulant (warfarin, factor Xa inhibitor) - Coagulopathy - Chronic renal failure - Patients with hypersensitivity to this drug or its components

Design outcomes

Primary

Measure	Time frame
Transfusion	—

Secondary

Measure	Time frame
Hemoglobin level	—

Countries

Korea, Republic of

Contacts

Public ContactSeung Bin Im

Seoul National University Hospital

euryword@naver.com+82-2-2072-2368

Outcome results