None listed
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Children with atopic dermatitis between the ages of 6 and 16 (case group) and age, sex-matched children without atopic dermatitis (control group). The proportion between case and control group is 3:1. 1) Case group is defined as children who diagnosed with a pediatric allergist on the basis of Hanifin & Rajka criteria. 2) Control group is defined as children who have never been diagnosed AD.
Exclusion criteria
Exclusion criteria: 1. If they used systemic corticosteroid or immunosuppressant within 4 weeks 2. If they had acute exacerbation of allergic diseases or skin diseases other than atopic dermatitis 3. If they had dyspnea or wheezing on the experimental day. 4. If it is hard to carry out studies because of the investigator judgement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| skin temperature;skin pH;transepidermal water loss;filaggrin protein;filaggrin degradation products | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin prick test | — |
Countries
Korea, Republic of
Contacts
Samsung Medical Center