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Association between ?2A-adrenergic receptor genetic polymorphism and sedative effects of dexmedetomidine

Association between ?2A-adrenergic receptor genetic polymorphism and sedative effects of dexmedetomidine

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0003947
Enrollment
133
Registered
2019-05-20
Start date
2018-05-31
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Pusan National University Yangsan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ASA class I - III, adult patient over 18 years of age undergoing elective angioplasty for peripheral vascular disease under general anesthesia

Exclusion criteria

Exclusion criteria: ? ASA class IV and up ? emergency surgery ? major coagulopathy expected to increase risk of major bleeding episode due to ultrasound-guided sciatic & femoral nerve blocks ? lack of cooperation to perform ultrasound-guided procedures ? lack of medicatl records (esp. Ankle Brachial Index)

Design outcomes

Primary

MeasureTime frame
time to achieve moderate sedation level (onset)—

Secondary

MeasureTime frame
genetic polymorphism of a2-adrenergic receptor A subtype—

Countries

Korea, Republic of

Contacts

Public ContactJu Yeon Park

Pusan National University Yangsan Hospital

monojp@naver.com+82-55-360-2129

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026