Endoscopic treatment for gastroesophageal reflux disease

Clinical outcomes of anti-reflux mucosectomy (ARMS) for gastroesophageal reflux disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0003938

Enrollment

Registered

2019-05-16

Start date

2019-06-01

Completion date

Unknown

Last updated

2019-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : In the GERD patients, the upper gastrointestinal endoscope is inserted through the oral cavity with conscious sedation. After submucosal saline injection into the cardia area, perf

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with gastroesophageal reflux disease who are not able to maintain pharmacotherapy or whose pharmacotherapy is inadequate and have a duration of six months or more

Exclusion criteria

Exclusion criteria: 1) Hiatal hernia more than 2 cm in length with upper endoscopic examination 2) LA-C or LA-D reflux esophagitis 3) Barrett`s esophagus >2cm 4) Esophageal varix 5) Gastric outlet obstruction 6) Spastic motility disorder such as achalasia, diffuse esophageal spasm, and Jack hammer esophagus with esophageal manometry 7) Coagulopathy (Platelet < 50,000, PT < 60%, unable to stop antiplatelet or anticoagulant such as aspirin/warfarin) 8) Pregnancy 9) Anatomic alteration due to previous esophageal or gastric surgery 10) Body mass index > 35

Design outcomes

Primary

Measure	Time frame
GERD symptom improvement;stricture	—

Secondary

Measure	Time frame
24 hour pH monitoring	—

Countries

Korea, Republic of

Contacts

Public ContactKee Don Choi

Asan Medical Center

keedonchoi@gmail.com+82-2-3010-5813

Outcome results