Randomized controlled study after ATN DBS for treatment of incurable epilepsy, to compare whether there is a difference in the effect of reducing epilepsy seizure among continuous or periodic methods of electric stimulation

A randomized controlled study of ATN DBS epilepsy treatment to assess the therapeutic superiority between cyclic and continuous mode in Korean epilepsy patients(ATTACK study)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0003899

Enrollment

Registered

2019-05-09

Start date

2018-04-30

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : To analyze the superiority of ATN DBS (continuous vs. periodic), the DBS treatment is administered in three different crossovers (open time) for three months each.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: A _ Patients aged 19 years and under 65 B _ Patients who have previously been diagnosed with drug-resistant epilepsy C _ Patients with more than two seizures a month, despite two or more anti-interesting medications. D _ Video brainwaves for regionalization of epilepsy and preoperational examinations (MRI, FDG PET, etc.) offer conflicting results without providing an accurate focus E _ Patients who are not adapted to surgical treatment due to anticipated neurological side effects or multiple epilepsy focal lesions

Exclusion criteria

Exclusion criteria: A _ Patient is unable to cooperate due to a confusion in the conscious state (below stupor) B _ Pseudoseizure is performed

Design outcomes

Primary

Measure	Time frame
Number of seizure	—

Secondary

Measure	Time frame
Change in cognitive function	—

Countries

Korea, Republic of

Contacts

Public ContactJungil Lee

Samsung Medical Center

jilee@skku.edu+82-2-3410-3494

Outcome results