Tranexamic acid in bilateral TKA

Combined administration of intravenous and topical tranexamic acid in bilateral Total Knee Arthroplasty : Is it the most effective regime? A Randomized controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0003849

Enrollment

630

Registered

2019-04-25

Start date

2015-08-26

Completion date

Unknown

Last updated

2019-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : A total of 630 patients undergoing bilateral TKA between April 2015 and May 2017 were randomized to four groups: simultaneous IA only (n= 157), simultaneous combined (n= 153), stag

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with a diagnosis of primary osteoarthritis (OA) scheduled for bilateral simultaneous or staged primary TKA

Exclusion criteria

Exclusion criteria: exclusion criteria were patients with a diagnosis other than primary OA, severe ischemic heart disease, coagulation disorders, pre-existing hepatic or renal dysfunction, a history of thromboembolic disease and those on anticoagulation therapy

Design outcomes

Primary

Measure	Time frame
total blood loss and blood transfusion rate after surgery	—

Secondary

Measure	Time frame
blood loss via the drain, postoperative hemoglobin drop, the proportion of patients with hemoglobin lower than 7.0, 8.0, and 9.0 g/dL, and the incidence of deep vein thrombosis (DVT), pulmonary embolism (PE) and wound complications including deep periprosthetic joint infection	—

Countries

Korea, Republic of

Contacts

Public ContactTae Kyun Kim

TK Orthopedic

osktk2000@yahoo.com+82-31-288-6822

Outcome results