Effects of Electrolyzed-Reduced Water(ERW) on the Activities of Antioxidant Enzymes in Healthy Adults: Randomized double-blind placebo-controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0003808

Enrollment

Registered

2019-04-18

Start date

2019-02-20

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others : Subjects are randomly assigned into two groups, with an ERW(Electrolyzed Reduced Water) group(n=32) and MW(Mineral Water) group(n=33) and educated to drink electrolyzed reduced water(Ph 9.00-

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Subjects who voluntarily agreed to participate and signed in informed consent (2) Healthy Volunteers 18-65 years old (include patients with controlled hypertension or diabetes mellitus)

Exclusion criteria

Exclusion criteria: (1) Smokers (2) Subjects who consume Alcohol more than 4 regular(250cc) cups of beers or 5 small (50cc) glasses of Korean distlled spirit(men) and more than 2 regular(250cc) cups of beers or 2.5 small (50cc) glasses of Korean distlled spirit for (women) and/or of drinking for more than 2 weeks (3) Pregnant Women (4) Uncontrolled diabetes mellitus (5) Uncontrolled High blood pessure (6) Subjects who implented Cardiac pacemaker (7) Subjects who taking Antioxidant supplements; vit C, vit E, flavonoids, bilberry, CoQ19, glutathione, omega-3, Mg, Mn, Zn ( 2 weeks of Wash-out period is needed before enrollement)

Design outcomes

Primary

Measure	Time frame
Biomarkers of Oxidative Stress: Antioxidant Enzymes (SOD(Superoxide Dismutase), GPX(Glutathione Peroxidase), CAT(Catalase)), MDA(Malondialdehyde), 8-OHdG(8-hydroxy deoxyguanosine), oxidized LDL, d-ROMs (Reactive Oxygen Metabolites- derived compounds), BAP (Biological Antioxidant Potential)	—

Secondary

Measure	Time frame
NK cell activity, A.G.E.(Advanced glycation end-product), Complete blood count and Biochemistry Profile;Bio-Impedance Analysis (Phase angle, body composition);heart rate variability (SDNN, RMSSD, PSI, TP, LF, HF, LF/HF);Cardio-ankle vascular index (CAVI);Short Form-36 Health Survey,Brief Encounter Psychosocial Instrument-Korean version,Brief fatigue inventory,Fatigue Severity Scale;Adverse events	—

Countries

Korea, Republic of

Contacts

Public ContactYOUNG AH CHOI

Bundang Jesaeng Hospital

Outcome results