Comparison of long-term effects on knee joint function between selective cox-2 inhibitor and naproxen + esomeprazole combination regimen after arthroscopic meniscus operation

Comparative study on long term knee function by postoperative pain control using medication between selective COX-2 inhibitor and naproxen + esomeprazole after arthroscopic meniscus operation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0003790

Enrollment

Registered

2019-04-16

Start date

2019-05-19

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Patients are assigned to two groups according to drug differences. Group 1 was treated with celecoxib 200 mg once daily for two weeks from the day following surgery and group 2 received naproxe

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients undergoing arthroscopic meniscus operation for meniscus injury 2) Adult patients aged 19 to 54 years 3) Patients with Kellgren-Lawrence grade II or less 4) Patients who pre-agreed to the study 5) Patients with a VAS score of 5 or more

Exclusion criteria

Exclusion criteria: 1) Patients undergoing surgery for other associated injuries other than meniscus in the affected knee 2) Patients with cartilage damage with Outerbridge grade III or IV 3) Patients with a history of allergy to NSAIDs 4) Patients with a mental disorder and are in cure 5) Patients with abnormal findings on hepatic function test, renal function test, hemoglobin level, etc. who can not take NSAIDs

Design outcomes

Primary

Measure	Time frame
IKDC subjective score;Lysholm knee score;VAS pain score	—

Countries

Korea, Republic of

Contacts

Public ContactMin Jung

Yonsei University Health System, Severance Hospital

jmin1103@yuhs.ac+82-2-2228-5679

Outcome results