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Pharmacodynamic model of effect-site concentration of propofol for loss of consciousness in the patients done chemotherapy.

Pharmacodynamic model of effect-site concentration of propofol for loss of consciousness in the patients done chemotherapy.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0003769
Enrollment
60
Registered
2019-04-15
Start date
2019-04-09
Completion date
Unknown
Last updated
2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Inje University Busan Paik Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - experimental group(C): Patients undergoing colorectal cancer surgery or intestinal reconstruction under general anesthesia, Patients with a history of chemotherapy within 12 months before surgery, aged 18 to 75 years, BMI 18-29 kg/m2, and American Society of. Anesthesiologists(ASA) physical status1, 2. - control group(N): Patients undergoing colorectal cancer surgery or intestinal reconstruction under general anesthesia, Patients without a history of chemotherapy before surgery, aged 18 to 75 years, BMI 18-29 kg/m2, and American Society of. Anesthesiologists(ASA) physical status1, 2.

Exclusion criteria

Exclusion criteria: Patients with neurological, neuropsychiatric history, taking sadatives, taking chronic alcohol, who is expected to be difficult to maintain airway, difficult to communicate, or with a history of chomotherapy before the surgery 13 months prior to surgery.

Design outcomes

Primary

MeasureTime frame
Median effective effect-site concentration of propofol causing loss of consciousness

Secondary

MeasureTime frame
Modified observer’s assessment of alertness/sedation scale

Countries

Korea, Republic of

Contacts

Public ContactSeunghee Ki

Inje University Busan Paik Hospital

emong0303@gmail.com+82-51-890-6520

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026