None listed
Conditions
Interventions
Medical Device : Among patients with acute exacerbation (sudden respiratory symptoms worsening within 1 month) of idiopathic pulmonary fibrosis and P/F ratio <300 (based on acute lung injury) within 7
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Registers the subject from the IRB passage day. Among older than 19 years IPF patients with acute exacerbations (sudden respiratory symptoms worsening within 1 month), Patients who agreed steroid pulse therapy and signed permission. 1) Selection Criteria - AE-IPF is diagnosed by the following criteria (1) Previous or current diagnosis of IPF (2) aggravation or dyspnea of unknown cause lasting less than one month (3) high-resolution computed tomography (CT) images showed peripheral usual interstitial pneumonia pattern and newly developed bilateral ground glass opacity and/or consolidation (4) deterioration not fully explained by heart failure or other fluids overload
Exclusion criteria
Exclusion criteria: 1) Pediatric patients under the age of 18 2) Failure to obtain agreement 3) In the case of other diseases affecting survival besides IPF (heart failure, cancer, etc.) 4) In addition to hypoxemia, other organ failure such as hemodynamic instability 5) Accompanying severe hemorrhagic disease 6) In cases where there is reason to exclude other opinions of the investigator 7) Older than 80 years old 8) History of hypersensitivity to dialysis or extracorporeal circulation 9) Cardiovascular disease 10) Pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of P / F ratio improvement;Changes for laboratory test;Survival time | — |
Countries
Korea, Republic of
Contacts
Public ContactJin Woo Song
Asan Medical Center
Outcome results
None listed