CPAP treatment in stroke patients with OSA

Continuous positive airway pressure treatment in subacute phase stroke with obstructive sleep apnea : Randomized Controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0003688

Enrollment

Registered

2019-03-29

Start date

2017-11-07

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : We performed bedside sleep examination using a portable polysomnography (Stardust II

Respironics Inc., Murrysville, PA, USA). The polysomnography is the gold standard test for SDB[40]. This multichannel device recorded the following diagnostic parameters: oxygen saturation, pulse rate

Respironics Inc.) at a pressure setting with a range from 8 to 12 cmH2O. Patients were defined as having received adequate treatment if they had maintained CPAP for an average of &gt

4 hours over 2 weeks.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: : (1) a diagnosis of cerebral infarction or hemorrhage in the brain by CT or MRI, (2) patients between 18 and 80 years of age, (3) patients admitted within 7 days to 6 months after stroke onset, and (4) patients who provided informed consent.

Exclusion criteria

Exclusion criteria: (1) a history of traumatic brain damage or brain tumor, (2) baseline oxygen saturation <95%, (3) the presence of acute or chronic cardiopulmonary diseases that affects pulmonary function, (4) presence of neuromuscular diseases (e.g., amyotrophic lateral sclerosis and myasthenia gravis), and (5) an unstable medical condition preventing completion of the clinical trial.

Design outcomes

Primary

Measure	Time frame
stroke severity (Korean version of the National Institute of Health Stroke Scale (NIHSS));functional ambulation categories(FAC), modified rankin scale(mRS), Berg Balance Scale(BBS), and Korean version of the modified Barthel index(MBI);Korean version of the Mini-Mental State Examination (K-MMSE);QOL was assessed using the EuroQol-5 Dimension.	—

Secondary

Measure	Time frame
the sleep examination data;Epworth Sleepiness Scale	—

Countries

Korea, Republic of

Contacts

Public ContactHowook Kim

Chungnam National University Hospital

bulam5630@naver.com+82-42-280-6971

Outcome results