The effect of using nefopam in patient controlled analgesia on postoperative nausea and vomiting in patient undergoing laparoscopic surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0003659

Enrollment

178

Registered

2019-03-25

Start date

2018-12-31

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : F group: fentanyl 20 ?/kg + ramosetron 0.6 mg + normal saline (total volume: 100ml) N group: fentanyl 10 ?/kg + nefopam 200mg + ramosetron 0.6 mg + normal saline (total volume: 100ml) PCA devi

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: ? Female patient aged 19 to 74 years undergoing scheduled gynecological laparoscopic surgery ? American Society of Anesthesiologist Physical Status I, II or III ? Moderate to severe PONV risk according to Apfel score(female gender, non-smoker, history of PONV, postoperative opioids)

Exclusion criteria

Exclusion criteria: ? BMI<18.5 kg/m2 or BMI >35 kg/m2 ? Uncontrolled DM (HbA1c > 6.5%) ? Patients with severe comorbidity who need to reduce the amount of fentanyl

Design outcomes

Primary

Measure	Time frame
PONV, PONV_VAS;vomiting	—

Secondary

Measure	Time frame
Pain score_VAS;Quality of Recovery 15;PCA comsuption	—

Countries

Korea, Republic of

Contacts

Public ContactYoonju Go

Kyung Hee University Hosipital at Gangdong

mayloo@naver.com+82-2-440-7809

Outcome results