None listed
Conditions
Interventions
Dietary Supplement : Subjects in the Control group should take 1 tablet of control food per time with plenty water once a day for 8 weeks orally.
Subjects in the Exp1 group (Low-dose, 300 mg/day) shou
Sponsors
TWOWINPHARMA
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Age between 20 and 65 years 2) Total Cholesterol level between 200 and 240 mg/dl 3) Provision of written informed consent
Exclusion criteria
Exclusion criteria: 1) Taking any medication influencing lipid metabolism, such as statin, fibrate, beta-blocker or others, within the prior month and a long term ingestion of natural product-based health supplements 2) Have following diseases; ? Uncontrolled high blood pressure (>140/90 mmHg) ? Two and half fold higher than normal levels of alanine transaminase (ALT) and aspartate transaminase (AST) ? A higher value of creatinine than 1.4 mg/dl ? Either hypothryroisdim or hyperthyroidism ? A cancer 3) Had history of famillial hypercholesterolemia 4) Had a body mass index (BMI) with either less than 18 kg/m2 or higher than 30 kg/m2 5) Had participated in other clinical trials within 1 months 6) Reported high alcohol intake (>30 g/day, 120 g/week) 7) Other diseases that the researcher decides inappropriate to participate in the test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Cholesterol;Triglyceride;HDL-Cholesterol;LDL-Cholesterol | — |
Secondary
| Measure | Time frame |
|---|---|
| Soluble vascular cell adhesion molecule (sVCAM-1);Intercellular Adhesion Molecule 1 (ICAM-1);Inflammation index (CRP, TNF-a) | — |
Countries
Korea, Republic of
Contacts
Public ContactSeon Mi Shin
Semyung University
Outcome results
None listed