Comparison of effects of fluid therapy with Plasma solution A vs. Normal saline in cardiac arrest patients

Randomized clinical trial of Plasma solution A vs. Normal saline for fluid resuscitation in post-cardiac arrest patients: pilot study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CRIS

Registry ID

KCT0003587

Enrollment

Registered

2019-03-06

Start date

2019-03-01

Completion date

Unknown

Last updated

2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : A Normal saline 3~4L intravenous infusion during CPR and initial 24hr after return of spontaneous circulation B Plasma solution A 3~4L intravenous infusion during CPR and initial 24hr after ret

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. adult(>19 yr) patients who visited the emergency room of Gachon University Gil Medical Center after out-of-hospital cardiac arrest 2. Patient who does not have exclusion criteria

Exclusion criteria

Exclusion criteria: ? No return of spontaneous circulation(ROSC) ? Death before 24 hr after ROSC ? Cardiac arrest caused by trauma (not including hanging injury) and poisoning, Cardiac arrest in pregnant patients ? Patients who have do-not-resuscitate orders, terminal cancer patient ? Patients with (alcoholic or diabetic) ketoacidosis ? No agreement of caregivers for this study ? Patient who was transferred from an outside institution after cardiopulmonary resuscitation ? Patients who have end-stage kidney disease or advanced chronic kidney disease with baseline estimated glomerular filtration rate of less than 30 mL min-1 1.73 m-2) ? Patients who have hypernatremia (>150 mEq/L), hyperkalemia (>5.5 mEq/L), or hyperosmolality (>320 mOsm/kg) ? Cardiac arrest caused by stroke

Design outcomes

Primary

Measure	Time frame
acid-base status, lactate, electrolytes, coagulation profile	—

Secondary

Measure	Time frame
1 month mortality, neurologic outcome	—

Countries

Korea, Republic of

Contacts

Public ContactJae-Hyug Woo

Gachon University Gil Medical Center

emmetalkiller@gilhospital.com+82-32-460-3901

Outcome results