None listed
Conditions
Interventions
None listed
Sponsors
Chung-Ang Univerisity Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All adult patients (=19 years) with out-of-hospital cardiac arrest irrespective of the cause of arrest who are unconscious after return of spontaneous circulation (Glasgow Coma Scale score <8) and treated with targeted temperature management.
Exclusion criteria
Exclusion criteria: (1) Patients’ age<19 years (2) Patients who are dead on arrival to the hospital and do not receive cardiopulmonary resuscitation (CPR) (3) Patients who do not achieve return of spontaneous circulation (ROSC) in spite of CPR (4) Patients who do not receive targeted temperature management in spite of achieving ROSC (5) Patients who were diagnosed as end-stage renal disease with dialysis (peritoneal dialysis or hemodialysis) before developing cardiac arrest (6) Patients who have Do-Not-Attempt-Resuscitation order (7) Patients who have acute intracranial hemorrhage or acute ischemic stroke (8) Patients who have active bleeding (9) Patients’ legal surrogates refuse to participate the study or withdrawal of informed consent during the study period by patients’ legal surrogates or patients’ themselves (10) Patients’ legal surrogates cannot speak Korean.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The date of acute kidney injury development and recovery which is calculated since the day of achieving return of spontaneous circulation | — |
Secondary
| Measure | Time frame |
|---|---|
| Arrest location (home, workplace, sports or recreating, street or highway, public building, nursing home, and educational institution);Bystander cardiopulmonary resuscitation (yes or no);First monitored rhythm (ventricular fibrillation, pulseless ventricular tachycardia, pulseless electrical activity, and asystole);The date of expiration if patients expire at 30th day since return of spontaneous circulation;Daily serum creatinine level (mg/dL, if the serum creatinine level will be checked two or more times in a day, highest value will be recorded);Renal replacement therapy (yes or no);The type of renal replacement therapy (continuous renal replacement therapy or hemodialysis);Date of renal replacement therapy (initiation, termination, and duration);Discharge date;Age (years);Sex (male or female);Weight (kg);Past medical history (hypertension, diabetes mellitus, heart failure, chronic kidney disease);Witnessed arrest (witnessed or not witnessed);Pathogenesis (medical, trauma, drug overdose, drowning, electrocution, and asphyxia);Response time (time interval from call to visit);Defibrillation time (time interval from call to the time the first shock);Epinephrine dose (mg);Coronary angiography (yes or no);Extracorporeal membrane oxygenation (yes or no);Targeted temperature of TTM (33°C or 36°C);Maintenance period of targeted temperature management (24 h or 48 h);Urine output (mL/kg/h) in intensive care unit (ICU);Event of shock (mean arterial pressure < 70 mmHg) after return of spontaneous circulation;Survival discharge (yes or no);Modified Rankin scale at discharge;Modified Rankin scale at 30th day since return of spontaneous circulation | — |
Countries
Korea, Republic of
Contacts
Public ContactJe Hyeok Oh
Chung-Ang Univerisity Hospital
Outcome results
None listed